I just transitioned the site from Crimson, a web font, to Georgia. The former was frustrating due to its extended loading times, and I found its hinting lacking in certain places. It looks beautiful on retina displays, but doesn’t hold up so well on lower-resolution displays. Unfortunately, the latter is still more prevalent than the former. It’s a challenge to balance the two when considering a site design, but fortunately, Georgia holds up well on high-resolution displays.
I found this good interview with Matthew Carter, designer of Georgia (and Verdana) in the process. I also re-discovered Georgia Pro, which I’d love to use on the site, but I’m still a little wary of web fonts.